Publications
Mechanism of Action
Phase 2a Clinical Trial of Mitochondrial Protection (Elamipretide) During Stent Revascularization in...
ReadCardiolipin and Mitochondrial Cristae Organization...
ReadRole of Cardiolipin in Mitochondrial Signaling Pathways...
ReadRole of Cardiolipin Alterations in Mitochondrial Dysfunction and Disease...
ReadGuiding Ageing Research Into Maturity...
ReadMitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle perform...
ReadIn vivo mitochondrial ATP production is improved in older adult skeletal muscle after a single dose ...
ReadOphthalmic/Dry Age-Related Macular Degeneration/Leber Hereditary Optic Neuropathy
Phase 1 Clinical Trial of Elamipretide in Intermediate Age-Related Macular Degeneration and High-Ri...
ReadPhase 1 Clinical Trial of Elamipretide in Dry Age-Related Macular Degeneration and Noncentral Geogra...
ReadElamipretide Topical Ophthalmic Solution for the Treatment of LHON: Outcomes and Efficacy...
ReadEffects of the Mitochondria-Targeted Drug Elamipretide on Leakage-Independent Vision Loss in Fellow ...
ReadMechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration...
ReadAssociation of Ellipsoid Zone Integrity and Treatment Response in Non-Neovascular AMD Treated With S...
ReadOrphan Cardiomyopathy
Barth syndrome cardiomyopathy: targeting the mitochondria with elamipretide...
ReadA phase 2/3 randomized clinical trial followed by an open-label extension to evaluate the effectiven...
ReadTAZPOWER Analysis: Elamipretide Significantly Improves Disease Symptomatology versus Natural History...
ReadChanges in Plasma and Urinary Metabolites After Elamipretide in Barth Syndrome Patients: Analyses fr...
ReadTAZPOWER: Biomarker Cardiolipin Ratios and Clinical Symptom Severity from a Randomized, Double-Blind...
ReadTAZPOWER: Study Design of a Randomized, Double-Blind, Placebo-Controlled Crossover and Extension Tri...
ReadNew Targets for Monitoring and Therapy in Barth Syndrome...
ReadBloodspot Assay Using HPLC–Tandem Mass Spectrometry for Detection of Barth Syndrome...
ReadBarth Syndrome: From Mitochondrial Dysfunctions Associated with Aberrant Production of Reactive Oxyg...
ReadBarth Syndrome: Cellular Compensation of Mitochondrial Dysfunction and Apoptosis Inhibition Due to C...
ReadElamipretide Improves Mitochondrial Function in the Failing Human Heart...
ReadElamipretide Treatment in an Infant with Sengers Syndrome...
ReadElamipretide in Patients with Barth Syndrome: A Randomized, Double Blind, Placebo-Controlled Clinica...
ReadNeurology
The Mitochondria-targeting Peptide Elamipretide Potentiates Dystrophin Expression Induced by an Exon...
ReadThe mitochondrial targeted peptidomimetic SBT-272 protects corticospinal motor neuros with mutant TD...
ReadThe Cardiolipin-Targeting Compound SBT-272 Attenuates Neurodegeneration, Delays the Onset of Neurolo...
ReadThe mitochondrial targeted drug SBT-272 attenuates dopaminergic neuron loss, alpha-synuclein burden ...
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